Vikhroli Cell Biology Analyst Maha

Job description

Execute drug screening assays, maintain tissue cultures, deliver data to cross-functional teams, and contribute to assay capabilities while adhering to quality standards and timelines. Key Accountabilities (1/6) Perform drug screening in various assays Conduct screening of drugs or combinations in assays such as cytotoxicity, cell proliferation, and permeability Ensure adherence to standardized protocols while performing these tests Analyze generated data for accuracy and reliability to provide valuable scientific insights supporting Cipla's goals Key Accountabilities (2/6) Maintain tissue culture facility and cell lines Ensure the preservation and upkeep of at least five designated cell lines Regularly monitor and manage proper storage, maintenance, and culture conditions to maintain cell viability Proactively identify improvements for tissue culture processes to uphold high-quality standards Key Accountabilities (3/6) Submit scientific data to cross-functional teams Compile, analyze, and submit assay-generated data to teams such as formulation, regulatory affairs (RA), and Ciptec Collaborate with diverse internal stakeholders to ensure timely, efficient, and high-quality delivery of results aligned to project objectives Present updates on routine activities to senior managers Prepare and deliver monthly presentations of data generated during routine laboratory activities Highlight assay throughput, tissue culture performance, and on-time delivery metrics to showcase progress and provide actionable insights for decision-making Key Accountabilities (4/6) Support logistics and inventory management for laboratory operations Plan procurement activities, maintain inventory accuracy, and negotiate with vendors to ensure cost-effective purchasing of laboratory chemicals and consumables Schedule and monitor quarterly calibration of instruments, supporting uninterrupted project execution and driving operational efficiencies Key Accountabilities (5/6) Key Accountabilities (6/6) Major Challenges • Ensuring timely data submissions amidst potential delays in procurement or availability of lab chemicals and consumables • , Minimizing disruptions to research projects caused by facility or equipment breakdowns by proactively scheduling regular maintenance and AMC Key Interactions (1/2) Internal Formulators/API groups for sample submission when required • Procurement teams for generating purchase orders on a daily basis• , Accounts departments for releasing payments monthly • IT support for resolving computer and software-related issues weekly • Safety and engineering teams for lab maintenance as needed Key Interactions (2/2) External CROs for sample analysis performed on LC-MS/MS (monthly) • , Vendors for procurement of laboratory requisites (daily)• , Collaborators for scientific insights (weekly) • , Service engineers for installation, validation, and regular maintenance of instruments (monthly) Dimensions (1/2) Assay Throughput: 75 screenings annually • Tissue Culture Management: 5 cell lines maintained • Data Submission Timeliness: 90% on-time delivery • Instrument Calibration Frequency: Quarterly schedule maintained • Cost Savings from Procurement: 15% YoY improvement • Caco-2 Permeability: 10-20 drugs annually • PAR-4 Project: 25 compounds screened annually • Toxicity Studies: 20 compounds annually • Mechanism of Action Studies: 20 drugs annually Dimensions (2/2) Key Decisions (1/2) Decisions Acquisition of new laboratory instruments and equipment • Selection of vendors based on service quality and cost-effectiveness • Identification of training requirements for new assay development and technology Key Decisions (2/2) Recommendations Suggest improvements or developments in assay techniques to enhance laboratory capabilities • Provide inputs regarding critical equipment investments and lab safety upgrades Education Qualification Skills & Knowledge: Postgraduate degree in Biotechnology, Life Sciences, or related fields., 0–5 years of experience in cell culture activities and drug screening methodologies, with demonstrated teamwork and communication skills. 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