Senior Scientist, Computational Biology Expert
GlaxoSmithKline · Italy - Siena
Job description
Scope: • Perform bioinformatics tasks to identify, design and/or optimize protein-based prophylactic or therapeutic candidates (antigen vaccine candidates, monoclonal antibodies, …) • Perform customized, state-of-the-art bioinformatics analyses and interpret results in support of transversal GVGH research activities, such as complex pathogen sequence analyses In this role, You will: Responsible for the design of protein-based vaccine antigens by performing literature reviews, complex bioinformatics analyses, and structural prediction and analysis; Responsible for providing expert input into the analysis and interpretation of experimental results related to protein engineering, production, and purification, together with molecular biology and chemist experts; Responsible for proactively identifying, developing, and implementing innovative computational technologies related to the job purpose (e.g., writing scripts, optimizing and developing digital tools, and implementing software and digital packages from external sources) Support overall digital innovation within GVGH; Provide scientific support to the whole GVGH community for all computational biology-related analyses, including complex/big data analysis; Responsible for developing scientific reports related to the job purposes and providing support for the development of IP and regulatory submission files; May coordinate or manage students, scientists, and technicians involved in job-related activities; Ensure the highest ethical standards, good scientific practices and data integrity are implemented in daily work activities, as well as timely data collection and reporting in the area of responsibility; Why You? Basic Qualifications We are looking for professionals with these required skills to achieve our goals: Ph.D. or equivalent experience in Bioinformatics, Computational Structural Biology, data science, Engineering, Genetics, or a similar discipline with a strong focus on analysis and biological interpretation of bioinformatics data. 3+ years of work experience in a similar role; Genome, gene, and protein sequence analysis and annotation; integration of theoretical and experimental data to support gene expression optimization; Protein structure prediction, design and analysis; Proficient in the use of bioinformatics and protein structure computational tools (such as AlphaFold, PyMOL, Chimera, MOE, Schrödinger, Rosetta,..) to support the identification, design and optimization of protein antigens Proficient in the use of molecular dynamics tools such as AMBER or equivalent softwares; Proficient in scripting and programming in languages such as those of Python, Perl, or R to develop and implement analysis pipelines or optimize available tools; Fluent English (both written and spoken). Preferred Qualifications & Soft Skills Please note the following skills are not necessary, just preferred; if you do not have them, please still apply: Experience with complex/big data analysis would be a plus; Excellent interpersonal and communication skills, and the ability to work in complex matrix organizations and effectively collaborate with internal GVGH/GSK as well as external partners; Fluency in English is a must & fluency in Italian would be a plus. What we offer: Permanent contract in a very Inclusive environment Flexible Benefits Company Healthcare Plan Integrative pension fund Employee Assistance Programme Prevention services and vaccination clinic Tax assistance Local nursery agreement Postal service, laundry, shoe repair and tailoring On Site Gym On Site canteens and coffee corners Free company bikes and shuttle Closing date for applications: 14 July 2026 Please take a copy of the Job Description, as this will not be available post closure of the advert. When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application. Italian Salary Range / Fascia retributiva in Italia: EUR 47,025 to EUR 78,375The annual gross base salary range for new hires in this position is listed above for each applicable location. These ranges take into account a number of factors including the candidate’s skills, experience, education level and the market rate for the role. In addition, this position may offer an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. More detailed information on the total benefits package will be supplied during the recruitment process. This role is available for applicants from multiple locations, and therefore salary ranges for certain locations are also shown. Salary ranges for other locations are shown because some markets have pay transparency laws that require salary information on job postings, and those locations are potential job sites for this role. If salary ranges are not displayed in the job posting for a specific location or country, the relevant compensation will be discussed during the recruitment process. Please note salaries vary by country based on the candidate’s skills, experience, education level and the market rate for the role. Offers are typically made within the advertised range based on the candidate’s skills, experience and qualifications, with the upper end generally reserved for highly experienced candidates or other exceptional circumstances aligned with these criteria.La fascia salariale della Retribuzione Annua Lorda (RAL) per i nuovi assunti in questa posizione è indicata sopra per ciascuna sede applicabile. Queste fasce tengono conto di diversi fattori, tra cui le competenze, l'esperienza, il livello di istruzione del candidato e le condizioni di mercato per il ruolo. Inoltre, questa posizione potrebbe prevedere un bonus annuale e la partecipazione al nostro programma di incentivazione a lungo termine basato sull’assegnazione azioni, in funzione del livello del ruolo. Informazioni più dettagliate sull’intero pacchetto retributivo e sui benefit saranno fornite durante il processo di selezione. Questo ruolo è aperto a candidati basati in diversi paesi; per tale motivo sono indicate le fasce retributive relative a ciascun paese. La pubblicazione di tali fasce, per altri paesi, che sono possibili sedi lavorative per questa posizione, risponde a normative locali in materia di trasparenza retributiva, che richiedono l’indicazione delle retribuzioni negli annunci di lavoro. Qualora per una specifica sede o paese non sia indicata una fascia retributiva, le relative condizioni economiche saranno discusse nel corso del processo di selezione. E’ importante considerare che le retribuzioni variano da paese a paese in base alle competenze, all’esperienza, al livello di istruzione del candidato e alle condizioni di mercato per il ruolo. Le offerte vengono generalmente formulate all’interno della fascia indicata, tenendo conto delle competenze, dell’esperienza e delle qualifiche del candidato; il limite superiore è di norma riservato a candidati con un’esperienza particolarmente consolidata o a circostanze eccezionali coerenti con tali criteri. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale. People and patients around the world count on the medicines and vaccines we
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