Research Associate in Ophthalmology

Job description

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The PositionAt Roche, we believe it is urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients’ lives and we are ambitious in both decision and action. We commit ourselves to scientific rigor, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow. Roche Pharma Research and Early Development (pRED) is in constant evolution. We are now looking for a highly motivated Research Associate who will contribute to the development and application of human-relevant bioassays. The Research Associate will join our Ophthalmology Discovery Department located in Basel, Switzerland. This group has a robust early development portfolio in both retinal and anterior segment diseases and works closely with internal and external experts across many specialties. The opportunity:In this role, you will have the unique opportunity to contribute to cutting-edge ophthalmic research. Your main focus areas will include: Design, plan, and execute experiments; analyze data. Establish functional cellular assays, 2D and/or 3D cell culture systems for disease relevant models of ocular diseases. Perform cell engineering via nucleic acid-based modalities. Apply state-of-the-art molecular biology techniques for in vitro and ex vivo analysis such as: - ex-vivo tissue processing for FACS and OMIC analyses - protein analyses and tissues preparation (Western blot, ELISA, FACS, Luminex, immunohisto-/ cytochemistry) - histology - expression profiling (qPCR, scRNA/snRNA library preparation) - microscopy and image analysis (confocal and fluorescence microscopy, high content imaging) Develop, characterize, and apply advanced in vitro microphysiological systems such as spheroids, organoids, organ-on-chip, iPSC-derived cells. Who You are:3+ years of experience in a research lab and a MSc or BSc degree in a related scientific field, lab associate or similar education. The ideal candidate is scientifically curious, intellectually driven, and eager to learn and apply innovative research tools, including advanced human cellular models and molecular analyses at cellular resolution. Should demonstrate a 'can-do' attitude, be proactive in acquiring new skills, and possess strong critical thinking and effective communication abilities. Proficiency in standard lab equipment, data analysis and storage tools (e.g., GraphPad Prism, electronic lab notebooks, G Suite). Excellent skills in cell culture and tissue-derived cell isolation are essential. You are a motivated research associate with excellent scientific, communication and organizational skills, fully committed to team effort but able to work independently. Are you ready to apply? We are looking for a person who thinks beyond the job offered - someone who knows that this position can be a rare springboard to many other opportunities at Roche. Roche embraces diversity and equal opportunity in a serious way. We are committed to building teams that represent a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be. Roche is an equal opportunity employer. Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together. Roche is an Equal Opportunity Employer.