Senior Associate Scientist, Gene Engineering and Delivery

Job description

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us. The Cell Therapy Thematic Research Center is one of BMS’s differentiated research platforms delivering innovative therapies to patients. Our mission is to drive leadership in the use of cellular therapies to harness the power of the immune system in treating hematologic malignancies, solid cancers, and autoimmune disease. More specifically, our discovery and translational scientists are focused on developing next-generation, engineered cell-based therapies. The team is committed to discovering and developing transformative therapies that harness the power of the immune system to improve patient outcomes. Position Summary: The Gene Engineering and Delivery team in the Cell Therapy Thematic Research Center is seeking a highly motivated scientist to advance next-generation cancer immunotherapies through molecular design, viral vector engineering, and gene delivery innovation. This role will focus on designing, cloning, characterizing, and producing viral vector constructs that enable development of CAR T cell therapies. The ideal candidate brings strong molecular biology expertise, hands-on cell culture experience, and a collaborative, problem-solving mindset in a fast-paced research environment. Key Deliverables: Execute molecular design and cloning of complex DNA constructs for cell therapy applications. Demonstrate competency in mammalian cell culture, transfection, and transduction of primary T cells. Develop molecular engineering designs and assays that support gene delivery and viral vector characterization. Produce viral vectors to enable gene delivery workflows and experimental evaluation. Position Responsibilities: In the role as a Senior Associate Scientist within the Gene Engineering and Delivery team, the ideal candidate will: Design and clone DNA constructs to support CAR T cell therapy development. Culture mammalian cell lines for viral vector production, assessment, and gene delivery applications. Set up and run molecular characterization and cellular assays to evaluate viral vector performance. Develop, optimize, and document viral vector production and characterization protocols. Designs and executes experiments based on protocols. Collaborate with team members to assess the technical feasibility of novel gene delivery methods. Analyzes and interprets experimental data. Works within established procedures and in loosely defined problem-solving situations. Actively participates in troubleshooting of routine problems and initiatives related to continuous improvement or development of new approaches/technologies. Works under minimal supervision for both routine activities and non-routine activities. Makes decisions that impact own work and other group/team members. Participates on program/project teams, as needed. Maintain accurate, detailed electronic laboratory notebook records and supporting documentation. Summarize and present data in group meetings and written reports. Experience = Basic Qualifications: Bachelor’s Degree 4+ years of academic and / or industry experience Or Master’s Degree 2+ years of academic and / or industry experience Preferred Qualifications: B.S./B.A. degree in a scientific discipline and 2+ years of hands-on experience in relevant field of research Exceptional molecular biology skills, including molecular assay development, molecular design and cloning of complex DNA constructs, PCR, RT-PCR, and mRNA and DNA preparation. Experience with tissue culture techniques, including transfection of mammalian cell lines and transduction of T cells. Excellent organization, time management, and problem-solving skills with strong attention to detail. Ability to independently design and troubleshoot experiments Outstanding written, visual, and oral communication skills #LI-Onsite If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career. Compensation Overview: Seattle - WA: $102,570 - $124,290 The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/. Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include: Health Coverage: Medical, pharmacy, dental, and vision care. Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP). Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support. ​Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day. All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown. *Eligibility Disclosure: The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program. Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employe