Senior Expert Science & Technology – Downstream Process Development & Modelling (m/f/d

Job description

Salary Range: €46,550.00 - €86,450.00 Band Level 4 Job Description Summary As an Expert of Science & Technology in Downstream Process Development, you will play a key role in advancing model‑based development and decision making for biologics purification processes. You will develop, apply, and deploy mechanistic and hybrid models with a strong focus on covering downstream unit operations and their interconnection into integrated process flows. This role combines deep scientific expertise, hands‑on experience in the experimental work, design, execution of process development activities, building and adopting AI fluency and digital implementation. As a Science & Technology Expert, you will play a key role in advancing the development and optimization of biologics processes through process modeling, advanced analytics, data science, and artificial intelligence. You will develop and implement mechanistic and data-driven models to improve process understanding, predict process behavior, support decision-making, accelerate development, and enhance process robustness and technology transfer to manufacturing. You will work closely with project teams, process development scientists, data scientists, and manufacturing stakeholders, and you will be an active member of a global modelling community shaping the future of downstream development at Novartis. Job Description Senior Expert Science & Technology – Downstream Process Development & Modelling (m/f/d) Location: Mengeš, Slovenia #hybrid (12 days per month onsite) We are the DSP department focused on the development of drug substances, leveraging advanced technologies, science-based approaches, and digital solutions to design and optimize processes for manufacturing scale, contributing to the delivery of high-quality, safe, and effective medicines.. In this role, you will: Develop, identify, and apply downstream process models for biologics processes, with a strong emphasis on chromatography and their underlying physicochemical principles. Extend modelling approaches to other downstream unit operations to support process understanding and optimization. Design, plan, and execute laboratory experiments to generate high‑quality data for model development, calibration, and validation, working hands‑on in the lab when required. Apply modelling to support process design, scale‑up, troubleshooting, process robustness evaluation, and decision making across development stages. Implement and deploy models using scientific programming languages and advanced modelling tools or environments (e.g., Python, CADET, MATLAB, or similar), including development of user-friendly tools or applications for broader adoption Translate complex modelling results into clear, actionable insights for multidisciplinary audiences, including process scientists, project leaders, and management. Collaborate and communicate effectively with internal and external stakeholders, ensuring alignment between modelling activities, experimental work, and project objectives. Actively contribute to and help shape the global modelling community, sharing best practices, methodologies, and innovations. Contribute to scientific documentation, technical reports, and regulatory‑relevant deliverables as required. Education & experience MSc, PhD, or equivalent experience in Chemical Engineering, Biochemistry, Physics, Bioinformatics, Biomedical engineering, or related engineering or natural science discipline. Strong background in process modelling and/or Scientific computing. Strong, hands-on expertise in downstream process development, including mechanistic understanding of separation phenomena and demonstrated focus on process modelling. Technical expertise Proven experience in downstream process modelling, parameter estimation, scale‑down/scale‑up concepts, and integration of multiple unit operations. Ability to design and run experiments to support model development and validation. Strong programming skills in Python or similar, with experience in building reusable tools, workflows, or applications for broader user groups. Familiarity with data analysis, visualization, and model deployment concepts into practical use. Experience in Data Science and strong interest to build AI fluency within DSP team and across business funtions. Excellent communication skills, with the ability to dive deep into topics, understand both scientific needs and business perspectives, and effectively translate them into clear, actionable solution and strategies. With the selected candidate, we offer permanent employment with 6 months of probation period. Submit your application with your CV in both Slovenian and English. Benefits & Rewards At Novartis, we’re committed to reimagining medicine together - and rewarding the people who make it happen. Expected Annual Base Salary Range for role: €46,550.00 - €66,500.00 - €86,450.00 EUR Annual The base salary offered is determined based on gender-neutral objectives, such as relevant skills, competencies and experience in accordance with the Novartis pay setting policy and upon joining Novartis will be reviewed periodically. In addition to your base salary, you may be eligible for a performance-based bonus depending on certain performance parameters. The rewards of being part of our team go far beyond base pay and incentives. We also offer a variety of competitive benefits in kind to help you thrive personally and professionally, such as insurance plans, retirement plans, wellbeing resources and global recognition programs. In addition, we provide flexible and hybrid working options, where possible, and minimum 14 weeks paid parental leave. In addition to your base salary, you may be eligible for a performance-based bonus depending on certain performance parameters. Long-term equity awards granted at group level may also be part of your package. Further details will be provided during the application process. Pay equity is a fundamental principle of our employment policy and reflects our commitment to create a diverse, equitable and inclusive environment that treats all employees with dignity and respect, as outlined in our Code of Ethics. Read our brochure to learn more about our global total rewards offering: https://www.novartis.com/sites/novartis_com/files/novartis-life-handbook.pdf Note: Benefits and compensation may vary by country and are subject to local legal requirements, including provisions of collective bargaining agreements where applicable. A full overview of your compensation package, including any relevant collective bargaining agreement details applicable to your role based on your employment location and Novartis employer entity, will be communicated separately to you during the application process. Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve. Senior Expert Science & Technology – razvoj procesov čiščenja učinkovin in modeliranje procesov Povzetek opisa delovnega mesta (m/ž/d) Lokacija: Mengeš, Slovenija #hybrid Smo oddelek DSP, osredotočen na razvoj učinkovin, pri čemer uporabljamo napredne tehnologije, znanstveno utemeljene pristope in digitalne rešitve za načrtovanje in optimizacijo procesov za proizvodno merilo ter tako prispevamo k zagotavljanju visokokakovostnih, varnih in učinkovitih zdravil za bolnike. Namen delovnega mesta: Kot strokovnjak za znanost in tehnologijo na področju razvoja procesov čiščenja učinkovin boste imeli ključno vlogo pri napredku modelno podprtega razvoja in odločanja za procese čiščenja bioloških zdravil. Razvijali, uporabljali in uvajali boste mehanistične in hibridne modele, s posebnim poudarkom na procesnih enotah čiščenja učinkovin in njihovi medsebojni povezanosti v integrirane procesne tokove. Ta vloga združuje poglobljeno znanstveno strokovno znanje, praktične izkušnje z eksperimentalnim delom ter načrtovanj