
Head Of Science Operations
Sigma-Aldrich · Billerica, Massachusetts, United States
Applications are made on Sigma-Aldrich's own site. We never sit in the middle.
Job description
Work Location: Billerica, Massachusetts Shift: No Department: EF-ST-IA AIDD Automation Recruiter: Anthony Johnson This information is for internals only. Please do not share outside of the organization. About AIDD AI & Automation in Drug Discovery (AIDD) at EMD is building and scaling AI-driven and automated discovery capabilities. We connect machine learning, computational science, and lab automation to enable closed-loop chemistry and biology experimentation and faster, higher-quality scientific decisions. In our Boston-area autonomous make-and-test lab, automated synthesis, analytical characterization, and biological readout come together to accelerate discovery. Your Role We are hiring a Head of Science Operations to lead the Make and Test engine at the heart of AIDD. Reporting directly to the head of AIDD, this is a senior scientific leadership role with direct responsibility for a team of medicinal and synthetic chemists, biologists, and automation scientists. . You will oversee end-to-end experimental design and execution quality, R&D timelines and roadmaps, SOPs and data integrity in addition to scaling the team, and serving as the scientific voice of AIDD to customers, partners, and stakeholders. Key Responsibilities Scientific ownership of Make and Test workflow Own experimental design and execution for autonomous chemical synthesis and biological testing, ensuring high-quality data, and timely results. Lab operations governance Develop and maintain SOPs, QC metrics, safe-lab practices, and data lineage; drive continuous improvement and compliance. Throughput, capacity, and resource planning Build and maintain capacity models; collaborate with Automation to scale workflows without compromising data integrity. Platform collaboration and roadmap input Prioritize scientifically impactful platform enhancements; translate lab needs into actionable requirements for software and automation teams. Build and manage scientific roadmap, ensuring adherence to timelines for assay onboarding and capability enhancements. External partnerships and vendor governance Manage scientific alignment with CROs, vendors, and academic partners; define SLAs, knowledge transfer, and quality controls. Talent, capability building, and culture Hire, onboard, and develop senior scientists in Chemistry and Biology; establish performance rhythms and cross-functional teamwork norms; scale team from 5 to 10. Who You Are: Minimum Qualifications PhD in Chemistry, Biochemistry, Pharmacology, Pharmaceutical Sciences, or a related field At least 8 years of relevant industry experience in pharma, biotech, or CRO, with a demonstrated track record of scientific leadership in discovery programs. Hands-on expertise in chemistry and/or biology assay development; proven ability to optimize complex workflows with data-driven decision making. Experience leading and developing science teams; ability to recruit, mentor, and retain senior scientific talent. Proven ability to communicate science clearly to customers, partners, and non-scientific stakeholders. Experience with lab operations governance: SOPs, QC metrics, data lineage, safety, and compliance in a high-throughput setting. Preferred Requirements Experience integrating Chemistry and Biology in an autonomous or closed-loop discovery setting. Familiarity with retrosynthesis tools, high-throughput chemistry platforms, and automated bioassay systems. Comfort with ELN/LIMS, data lineage, metadata schemas, and basic AI/ML data interfaces; ability to partner effectively with data and software teams. Prior external-facing or partner-facing scientific leadership for platform-scale programs. Experience with budget ownership, vendor management, and contract scoping in a scientific operations context. What We Offer A seat on the AIDD leadership team, shaping the scientific direction of a first-in-class autonomous drug discovery platform. Direct influence over how Chemistry and Biology science is designed, executed, and connected to AI/ML at scale. An interdisciplinary team with deep science, engineering, software, and data expertise, operating at the frontier of autonomous drug discovery Location This is a fully on-site role based in Billerica, MA. Travel is expected to be limited and mainly related to vendor interactions, partner engagements, or key scientific milestones. Pay Range: $159,300-$220,100 The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here . The Company is an Equal Employment Opportunity employer. No employee or applicant for employment will be discriminated against on the basis of race, color, religion, age, sex, sexual orientation, national origin, ancestry, disability, military or veteran status, genetic information, gender identity, transgender status, marital status, or any other classification protected by applicable federal, state, or local law. This policy of Equal Employment Opportunity applies to all policies and programs relating to recruitment and hiring, promotion, compensation, benefits, discipline, termination, and all other terms and conditions of employment. Any applicant or employee who believes they have been discriminated against by the Company or anyone acting on behalf of the Company must report any concerns to their Human Resources Business Partner, Legal, or Compliance immediately. The Company will not retaliate against any individual because they made a good faith report of discrimination.
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