Scientist, In Vivo Pharmacology

Job description

Working with Us Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us. The Cell Therapy Thematic Research Center is one of BMS’s differentiated research platforms delivering innovative therapies to patients. Our mission is to drive leadership in the use of cellular therapies to harness the power of the immune system in treating hematologic malignancies, solid cancers, and autoimmune disease. More specifically, our discovery and translational scientists are focused on developing next-generation, engineered cell-based therapies. The team is committed to discovering and developing transformative therapies that harness the power of the immune system to improve patient outcomes. Position Summary Bristol Myers Squibb is seeking a highly motivated Scientist to join the In Vivo Pharmacology group supporting Oncology and Immunology discovery programs. The successful candidate will play a key role in the design, execution, analysis, and interpretation of preclinical in vivo studies to evaluate novel therapeutic candidates. This position requires a strong scientific background in pharmacology, immunology, and/or oncology, as well as the ability to independently drive experimental strategies and collaborate within multidisciplinary discovery teams to advance programs from target validation through candidate selection. Position Responsibilities In the role as a Scientist within In Vivo Pharmacology, the ideal candidate will: In Vivo Study Execution (Oncology & Immunology) Design and interpret in vivo studies in murine models of cancer and immune-mediated diseases. Perform and oversee in vivo studies, including compound administration, disease induction, tumor implantation, immune cell transfers, longitudinal sampling, and animal monitoring. Develop experimental strategies to evaluate pharmacodynamic, efficacy, mechanism-of-action, and combination therapy hypotheses. Independently operate and apply imaging technologies, including IVIS, to support efficacy and mechanistic studies. Troubleshoot technical and scientific challenges and develop solutions to improve study outcomes. Contribute to the optimization and development of novel in vivo models and experimental workflows. Data Analysis & Reporting Analyze and interpret complex datasets using GraphPad Prism, Excel, and other data analysis tools. Integrate in vivo, pharmacodynamic, biomarker, and mechanistic data to generate actionable scientific insights. Maintain accurate and timely electronic laboratory notebook (ELN) documentation. Prepare and present study results, scientific reports, and project updates to cross-functional teams and leadership. Contribute to scientific publications, technical reports, presentations, and regulatory documentation as appropriate. Cross-Functional Collaboration Serve as an in vivo pharmacology representative on Oncology and Immunology project teams. Partner with external collaborators and contract research organizations (CROs) to support study execution and data interpretation. Contribute scientific insights to project strategy, portfolio discussions, and candidate advancement decisions. Laboratory Operations & Compliance Ensure compliance with BMS policies, IACUC regulations, and animal welfare standards. Maintain lab supplies, equipment, and study materials. Participate in continuous improvement of in vivo models and workflows. Experience = Basic Qualifications: Bachelor’s Degree 5+ years of academic and / or industry experience Or Master’s Degree 3+ years of academic and / or industry experience Or Ph.D. or equivalent advanced degree in the Life Sciences No experience necessary Preferred Qualifications: PhD in Pharmacology, Immunology, Oncology, Cell Biology, or a related life science discipline; or MS with 3+ years, or BS with 5+ years of relevant industry experience in in vivo pharmacology. Strong scientific expertise in preclinical in vivo pharmacology required. Demonstrated experience designing, executing, and interpreting studies in oncology and/or immunology disease models required. Hands-on experience with rodent handling, dosing techniques, and biological sample collection required. Experience with tumor models, immune-mediated disease models, or both required. Proficiency with IVIS imaging and associated data analysis required. Strong understanding of experimental design, statistics, and data interpretation. Excellent problem-solving skills and scientific curiosity. Strong written and verbal communication skills with the ability to effectively present scientific findings. Ability to manage multiple priorities and work effectively in a collaborative, fast-paced research environment. Industry experience in biotech or pharmaceutical R&D desired. Experience working in matrixed, cross-functional teams desired. Familiarity with imaging techniques, biomarkers, or molecular assays desired. #LI-Onsite If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career. Compensation Overview: Cambridge - MA - US: $128,380 - $155,571 The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/. Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include: Health Coverage: Medical, pharmacy, dental, and vision care. Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP). Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support. ​Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christ