FSP Senior Scientist - Antibody Engineering

Job description

Work Schedule Standard (Mon-Fri) Environmental Conditions Laboratory Setting, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.) Job Description Join us as Senior Scientist! At Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on – now and in the future. Our PPD® Laboratory Services team has a direct impact on improving patient health through the expertise of scientists, industry thought-leaders and therapeutic experts. As the world leader in serving science, our laboratory professionals bring their commitment to accuracy and quality to deliver groundbreaking innovations. As a Senior Scientist, your role will be to conduct advanced diagnostic tests, ensure the highest accuracy and reliability of laboratory data, mentor junior scientists, and drive continuous improvements in laboratory methodologies and quality standards. What You’ll Do: • Carry out laboratory functions, plan and design experiments and apply technical knowledge and skills to achieve project goals in a precise and timely manner. • Optimized protocols for yeast display, cell free protein synthesis to achieve better expression and higher sensitivity for antibody screening. • Identify and troubleshoot critical issues with screening assays, resolving them promptly to ensure consistent progress and quality. • Collaborate cross-functionally with automation group to coordinate antibody screening and align with biology scientists within company to ensure the antibodies are being tested on time. • Design and carry out secondary screening strategies using HTS liquid handlers. • Antibody affinity maturation, optimize humanization and improve antibody developability. • Keep accurate experimental documentation using Benchling and maintain well-organized inventory of antibodies and antigens. • Present data in antibody group meetings and project meetings. Education and Experience: • Bachelor's degree or equivalent and relevant formal academic / vocational qualification • Previous experience to provide the knowledge, skills, and abilities to perform the job (comparable to 4-6 years). In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role. • Strong background of molecular biology or biochemistry with good GPA. • Well understanding of antibody structure and function relationships. • Comprehensive protein engineering techniques. • Excellent communication skills and interpersonal skills with the ability to present scientific data in team meetings. • Demonstrated strong problem-solving and analytical thinking skills, showing a proactive attitude towards exploring new approaches. • Able to collaborate and help other scientists. Working Conditions and Environment: • Work is performed in a laboratory and/or a clinical environment with exposure to electrical office equipment. • Occasional drives to site locations, occasional domestic travel. • Exposure to biological fluids with potential exposure to infectious organisms. • Rare exposure to skin and lung irritants, radiation, toxic materials and hazardous waste. • Personal protective equipment is required such as protective eyewear, garments and gloves. • Exposure to fluctuating and/or extreme temperatures on rare occasions. Physical Requirements: • Ability to work in an upright and /or stationary position for 6-8 hours per day. • Repetitive hand movement of both hands with the ability to make fast, simple, repeated movements of the fingers, hands, and wrists to operate lab equipment. • Occasional mobility needed. • Occasional crouching, stooping, with frequent bending and twisting of upper body and neck. • Light to moderate lifting and carrying (or otherwise moves) objects including luggage and laptop computer with a maximum lift of 15-20 lbs. • Ability to access and use a variety of computer software developed both in-house and off-the-shelf. • Ability to communicate information and ideas so others will understand; with the ability to listen to and understand information and ideas presented through spoken words and sentences. • Frequently interacts with others to obtain or relate information to diverse groups. • Works independently with little guidance or reliance on oral or written instructions and plans work schedules to meet goals. Requires multiple periods of intense concentration. • Performs a wide range of variable tasks as dictated by variable demands and changing conditions with little predictability as to the occurrence. Ability to perform under stress. Ability to multi-task. • Regular and consistent attendance. Why Join Us? When you join Thermo Fisher Scientific, you become part of a global team that values passion, innovation, and a commitment to scientific excellence. You’ll work in an environment where collaboration and development are part of the everyday experience – and where your contributions truly make a difference. Apply today to help us deliver tomorrow’s breakthrough. Compensation and Benefits The salary range estimated for this position based in California is $34.00–$44.00. This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes: A choice of national medical and dental plans, and a national vision plan, including health incentive programs Employee assistance and family support programs, including commuter benefits and tuition reimbursement At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards