Manager, Global Logistics

Job description

Overview The Manager, Logistics Design & Cold Chain will support the development, implementation, and continuous improvement of global logistics design standards to help ensure product integrity across Alnylam’s end-to-end supply chain network. This role will contribute to packaging strategy, transportation lane design, temperature-controlled shipping requirements, and logistics risk mitigation in partnership with Global Logistics Operations, Quality, Validation, Clinical and Commercial Supply Chain, CMOs, 3PLs, and logistics service providers. This position will serve as a key operational and technical partner responsible for translating logistics design requirements into practical, scalable processes that support consistent, compliant, and reliable product movement. The role will focus on execution of defined logistics design initiatives, lane assessments, packaging and transportation standards, and continuous improvement opportunities across cold chain and broader temperature-sensitive logistics operations. This position is hybrid and will be primarily located in Cambridge, MA . Key Responsibilities Logistics Design & Network Governance Support the development and maintenance of global packaging and transportation strategies across various products, shipment types, and temperature profiles Partner with Packaging Engineering, Validation, Quality, and Operations to define lane routing, carrier selection, pack-out requirements, and lane design inputs Facilitate approval processes for packaging, validation and transportation configurations based on risk, performance and business needs Identify and mitigate logistics risks (lane variability, disruptions, packaging performance) and define contingency strategies Standards & Compliance Establish global standards for temperature control and environmental conditions across all shipment profiles Ensure alignment between packaging, validation, transportation strategy, and product requirements to maintain product integrity Facilitate the creation of logistics design policies, standards, and SOPs, and lead their implementation across assigned products, lanes, and logistics partners Ensure compliance with GDP/GMP and regulatory requirements in partnership with Quality & Validation Partner with internal teams and external providers to implement standardized logistics design practices across assigned products, lanes, or initiatives Risk Management Assess transportation and cold chain risks for assigned lanes, products, or logistics scenarios Support the development of risk-based mitigation plans in partnership with Packaging Engineering, Validation, Quality, and Logistics Operations Monitor lane and provider performance to identify potential product integrity or service reliability risks Cross-Functional Execution & Partner Engagement Serve as a logistics design and cold chain point of contact for assigned projects, lanes, or operational initiatives Collaborate with CMOs, 3PLs, logistics service providers, Quality, Validation, Manufacturing, Clinical Supply, Commercial Supply, and Trade Compliance Support cross-functional decision-making related to transportation design, packaging configuration, lane setup, and shipment readiness Continuous Improvement & Innovation Identify opportunities to standardize and optimize logistics strategies across the global network Drive improvements in service reliability, cost efficiency, and product protection Analyze shipment performance, lane data, excursion trends, and carrier performance to recommend improvements Evaluate and implement innovative technologies and solutions that enhance logistics performance and visibility Qualifications Bachelor’s degree in Supply Chain, Logistics, Life Sciences, or a related discipline Minimum 5 years o