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Sigma-Aldrich

MES Engineer

Sigma-Aldrich

Full-timeOn-sitePosted 7 October 2026
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Job description

Work Your Magic with us! Start your next chapter and join MilliporeSigma. Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us. This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US. Your Role The MES Engineer supports the effective use and continuous improvement of Siemens Opcenter Medical Device and Diagnostics MES at the Jaffrey site. This role provides day-to-day user and operational support, troubleshooting, business-facing configuration updates, and coordination with IT and cross-functional teams to help ensure MES supports site operations, quality, and compliance requirements. The role works closely with site SMEs, Operations, Quality, Validation, Automation, IT, and global digital teams, and may also support future MES expansion to additional lines and process as the program progresses. Key Responsibilities: Perform MES modeling and configuration changes and enhancements to address operational needs, improve user experience, and align system use with site processes and user requirements. Resolve workflow, reporting, integration, and usage issues in Opcenter MES, in collaboration with Opcenter SME and cross-functional teams. Work with IT to support resolution to issues affecting Production uptime as needed. Support integration between equipment and site/enterprise system interfaces by monitoring data flow, troubleshooting issues, and coordinating enhancements with cross-functional teams. Lead change management activities for all MES maintenance and improvement initiatives for existing deployments, with support from the cross-functional team. Perform change assessments and support qualification and validation activities for system updates, fixes, and enhancements Create and maintain technical documentation aligned with GAMP, SDLC, and site procedures Ensure MES-related activities comply with GxP, data integrity, EHS, and quality requirements Partner with Operations, Quality, Validation, Automation, IT, and other teams to support continuous improvement and effective site use of MES Who You Are Minimum Qualifications Bachelor’s degree in STEM, engineering, computer science, technical management, or other field , including Mathematics, Physics, Chemistry, Biology, Statistics, Mechanical Engineering, Electrical Engineering, Chemical Engineering, Industrial Engineering, Manufacturing Engineering, Systems Engineering, Computer Science, Software Engineering, Information Technology, Information Systems, Data Science, Computer Engineering, Technical Management, Engineering Management, Technology Management, Operations Management, or Project Management 2+ years of experience supporting manufacturing process, OT, MES, or related digital systems in a production environment Preferred Qualifications Experience in Siemens Opcenter MDD (Medical Device and Diagnostics) MES configuration, including modeling objects, business rules, expressions, user queries, integrations and batch records Basic knowledge of manufacturing process support and system troubleshooting Experience of SQL queries, SAP Business Objects, or related reporting and data tools Experience with equipment integration and enterprise system integration, interface support, including OPC UA or similar connectivity Working Knowledge of ISO & FDA regulations (such as ISO 9001, ISO 13485 or 21 CFR 820, 210 & 211). Understanding of GxP-regulated environments and GAMP requirements. Experience supporting system builds, upgrades, or enhancement activities in a validated manufacturing environment. Strong analytical, problem-solving, and communication skills Pay Range for this position: $87,000 - $130,400 The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here . What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress! Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!

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