Director, Translational Sciences-Immunology

Job description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit. Job Function: Discovery & Pre-Clinical/Clinical Development Job Sub Function: Translational Discovery & Development Biomarkers Job Category: Scientific/Technology All Job Posting Locations: San Diego, California, United States of America Job Description: About Innovative Medicine Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine About Immunology Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Our Immunology team leads in the development of transformational medicines for immunological disorders and illnesses. You can influence where medicine is going by restoring health to millions of people living with immune diseases. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. We are searching for the best talent for a Director, Translational Sciences (TS), Immunology Translational Sciences and Medicine (TSM) to be in San Diego, CA. Translational Science and Medicine (TSM) is an integrated group of scientists composed of a clinical Translational Medicine (TM) team which conducts early clinical development and experimental medicine studies, and a Translational Sciences (TS) team which uses human based data and tissues to support the end-to-end portfolio. Together, the TSM group will provide the key learnings/insights on the next wave of novel therapies. Organizationally, TSM serves as a pivotal bridge between Discovery Research and the later phase Clinical Development group. TSM provides the necessary scientific and clinical expertise to advance an industry-leading pipeline of novel mechanism small molecules and biologic agents to address unmet need in immune-mediated diseases. TS has a broad remit stretching from support of discovery with human data to support target selection, through development and implementation of decision- making biomarkers for early phase clinical trials, target-centric indication sequencing and prioritization, and support of regulatory filings and life cycle management. TS has expertise in biomarker development, disease biology research and in the application of immunology and data science technologies to support drug development. The Director, TS will be a leader in the Immunology Translational Science team focusing on drug discovery projects, the design and implementation of novel experiments and interpretation of data to lead in the clinical progression of innovative therapies across immunologic diseases. The successful candidate will be responsible for building and executing on the strategy to drive assets across the Immunology portfolio with an emphasis on Immuno-Dermatology diseases. The Director will lead and guide a team of bench scientists accountable for the design and execution of lab experiments for human skin-based stimulation models, new assay development and data interpretation. The candidate will bring an enthusiastic discovery mindset to Translational Sciences. The Director, TS will lead and develop a team of scientists responsible for the timely creation and implementation of high caliber translational biomarker plans in support of key milestones for preclinical and early phase clinical portfolio programs. The Director will also be responsible for the identification and validation of non-invasive skin biomarker technologies. Additional activities include partnering with Discovery, TM scientists and external partners to drive the strategy for disease understanding, target validation, and disease indication exploration. The Director will be expected to be proactive in support of decision making to project teams. He/she will be a member of the TS Extended Leadership Team which is responsible for leading the broader TS organization. Responsibilities are as follows: • Lead and develop a team of bench scientists • Accountable for the design and execution of translational science and biomarker plans integrating both disease and pathway approaches to support early Immuno-Dermatology portfolio programs • Lead efforts to identify and validate a suite of non-invasive biomarker technologies that can be deployed in clinical trials • Guide and develop team members to drive stakeholder management and communication of study results in the application of strategic decisions for programs • Work closely with key leaders in partner functions to ensure project goals are met • Ensure strong translational package for the evaluation of new target identification, target evaluation, and indication selection in collaboration with teams from discovery through to clinical development • Make recommendations for investment and leadership of key external collaborations Qualifications – External • Ph.D. with a minimum of 7-10 years of relevant experience is required, preferably in pharmaceutical or biotechnology sectors • Industry and/or translational research experience is required • Immunologist with breadth of lab expertise, including skin-based immunoassays, required • Immuno-dermatology (e.g., Psoriasis, Atopic Dermatitis) expertise is required • Creative, talented, problem-solving • Exceptional communication and collaboration skills are required • People management experience in a matrixed environment is preferred • Dynamic entrepreneurial mindset The anticipated base pay range for this position is: $164,000 - $276,000 The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation’s performance over a calendar/performance year. Bonuses are awarded at the Company’s discretion on an individual basis. Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. • Employees may be eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)). • This position is eligible to participate in the Company’s long-term incentive program. • Employees are eligible for the following time off benefits: • Vacation – up to 120 hours per calendar year • Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington – up to 56 hours per calendar year • Holiday p