Senior Biologist

Job description

About AQEMIA AQEMIA is a drug invention company dedicated to creating entirely new medicines to address major unmet medical needs. At the core of our mission is QEMI , our proprietary molecule-invention platform, which uniquely combines cutting-edge science with advanced technology. Powered by physics-based modeling, statistical mechanics, and generative AI, QEMI allows our teams to design novel drug candidates from first principles. What makes AQEMIA different is our commitment to true innovation: our research is dedicated to the invention of new molecular entities, not the refinement of existing ones. We focus on inventing never-before-seen molecules , without relying on experimental data, and advancing them into a growing pipeline of proprietary programs and strategic partnerships with leading pharmaceutical companies. Our most advanced preclinical programs are currently in vivo optimization , targeting diseases still waiting for effective treatments, offering our teams the opportunity to work on science that can make a real difference in people’s lives. For more information, visit AQEMIA.com , our WTTJ Page , and our LinkedIn . About our Team AQEMIA brings together a diverse, multidisciplinary team of 80+ professionals based in Paris and London. Our scientists and engineers, including chemists, physicists, machine learning experts, and software engineers, work side by side to push the boundaries of early-stage drug discovery. This close collaboration across disciplines is central to our approach, enabling us to tackle complex scientific challenges from first principles and translate cutting-edge ideas into novel therapeutic candidates. At AQEMIA, team members are encouraged to contribute their expertise, learn from one another, and play an active role in shaping the future of drug invention. About the Drug Discovery Team The Drug Discovery Sciences team combines expertise in medicinal chemistry, computational chemistry, biology, and translational science . Working at the intersection of AI-driven drug design, molecular simulations, and experimental science, the team is responsible for driving scientific excellence across Aqemia’s drug discovery programs and delivering clinical candidates. They develop and apply innovative methodologies ensuring that scientific insights translate into high-quality therapeutic opportunities. Partnering closely with Platform, Engineering, and Program teams, they play a critical role in advancing novel small-molecule therapeutics from concept to clinical candidate. The role Join Aqemia in a role where you will lead the biology of small molecule programs as they move rapidly from hit to lead, through lead optimization and towards candidate nomination. As we expand our portfolio across oncology and CNS, this is a unique chance to act as biology lead on a drug discovery project, working closely with medicinal chemists, computational scientists and AI specialists in a small, fast-moving team. You’ll own the project’s biology day to day, from screening cascade design and CRO-run experiments to data interpretation and recommendations to leadership at key decision gates. We’ll also count on you to bring your own ideas on how to differentiate our projects from competitors working on the same targets. Responsibilities • Act as biology lead on a drug discovery project, driving its biological strategy and progression from hit-to-lead through lead optimization • Design, implement, and maintain screening cascades to generate high-quality, decision-enabling in vitro and in vivo data • Sign off biological experiments and collaborate with external