Ballerup Head Of Translational Medicine And Early Development Denm 2750

Job description

Turn scientific promise into clinical progress. Build the proof-of-concept engine that helps LEO Pharma make smarter development decisions and bring meaningful innovation closer to patients. Shape what comes next How would you connect emerging biology, quantitative insights, and clinical expertise to shape the next generation of development programs? At LEO Pharma, you will lead Translational Medicine & Early Development, bringing together people, partners, and evidence to answer critical questions early. This is an opportunity to build capabilities, influence portfolio decisions, and connect scientific ambition with a clear path to clinical proof of concept. Your role You will build and lead an integrated proof-of-concept engine, translating biological hypotheses into clinically testable, quantitatively informed, decision-ready programs. Working across internal teams and external partners, you will establish mechanism-based rationales, meaningful patient strategies, and robust development plans. Your focus will be on generating the evidence needed to select doses, assess benefit–risk, and guide progression toward registrational studies. Your primary responsibilities will be to: Lead translational and early-development strategy across programs, developing people leaders and subject-matter experts. Partner with Science, Search & Innovation and clinical teams to design early-phase studies demonstrating target engagement, proof of mechanism, and patient relevance. Integrate biomarkers, patient stratification, quantitative pharmacology, and modelling and simulation to optimize doses, regimens, endpoints, and study designs. Support clinical due diligence and integration of externally sourced assets, building partnerships that strengthen translational capabilities. Shape regulatory and cross-functional evidence strategies, translating complex findings into clear recommendations for project teams and governance forums. You will also establish progression criteria and performance indicators that strengthen decision quality, evidence maturity, execution, and resource efficiency. Throughout early development, you will ensure efficacy hypotheses are considered alongside safety, tolerability, and therapeutic index. Your qualifications You bring scientific depth and leadership experience, with the ability to connect translational evidence to clinical and portfolio decisions. We are looking for: An advanced degree in Medicine, Pharmacology, Translational Science, Pharmaceutical Sciences, or a related discipline; MD and PhD qualifications are preferred. Significant leadership experience in translational medicine, clinical pharmacology, and/or early clinical development within biotech or pharma. Demonstrated expertise in early-phase studies in patients and healthy participants, linking mechanisms of action and biomarkers to dose selection and development strategy. A track record of building high-performing global teams, developing people, and integrating external assets and partnerships. Experience contributing to regulatory submissions and evidence generation supporting registration and market access. Experience with externally sourced innovation is strongly preferred; dermatology and/or rare-disease experience is beneficial. You combine strategic thinking with curiosity, sound judgment, and a collaborative approach, influencing effectively across a matrix organization. Your new team You will lead Translational Medicine & Early Development, with two line managers as direct reports, the group is in total 20 employees. You will report to the Vice President, Head of Global Clinical Development. Your network will span clinical development, skin science, regulatory, safety, market access, and commercial colleagues. Together with external collaborators, you will connect expertise across disciplines to strengthen early development. Contact and application For additional information, please contact Talent Acquisition Partner, Sabina Ravn Lebech at saleb@leo-pharma.com You do not need to upload a cover letter, but feel free to add a few sentences in your resume or CV on why this position has your interest. Beyond the skin Join LEO Pharma, a global leader in medical dermatology, as we go beyond the skin to make a lasting impact. Our innovative approach sets us apart. We are dedicated to leaving a legacy that positively impacts patients, colleagues, and our planet. At LEO Pharma, we believe in the power of individuals to drive change. Our flat organizational structure empowers you to make a visible impact and offers versatile roles for professional growth. We value diversity and welcome applications from all qualified candidates, recognizing that our different perspectives, backgrounds, and attitudes enable us to make the best decisions. Join our passionate team at LEO Pharma and be yourself as we work together to make a difference. For certain positions, LEO Pharma might complete a background check conducted by a third party. Report a concern: Whistleblower hotline | LEO Pharma Apply now » Find similar jobs: Opens in a new tab. Opens in a new tab. Opens in a new tab. Opens in a new tab. ©2024 LEO Pharma. All rights reserved. Cookie Consent Manager When you visit any website, it may store or retrieve information on your browser, mostly in the form of cookies. Because we respect your right to privacy, you can choose not to allow some types of cookies. However, blocking some types of cookies may impact your experience of the site and the services we are able to offer. Required Cookies These cookies are required to use this website and can't be turned off. Required Cookies Required Cookies Provider Description Enabled SAP as service provider We use the following session cookies, which are all required to enable the website to function: "route" is used for session stickiness "careerSiteCompanyId" is used to send the request to the correct data centre "JSESSIONID" is placed on the visitor's device during the session so the server can identify the visitor "Load balancer cookie" (actual cookie name may vary) prevents a visitor from bouncing from one instance to another Cookies from provider SAPasserviceprovider are required and cannot be turned off Functional Cookies These cookies provide a better customer experience on this site, such as by remembering your login details, optimising video performance or providing us with information about how our site is used. You may freely choose to accept or decline these cookies at any time. Note that certain functionalities that these third-parties make available may be impacted if you do not accept these cookies. Consent to all Functional Cookies Functional Cookies Provider Description Enabled YouTube YouTube is a video-sharing service where users can create their own profile, upload videos, watch, like and comment on videos. Opting out of YouTube cookies will disable your ability to watch or interact with YouTube videos. Cookie Policy Privacy Policy Terms and Conditions Consent to cookies from provider YouTube Advertising Cookies These cookies serve ads that are relevant to your interests. You may freely choose to accept or decline these cookies at any time. Note that certain functionality that these third parties make available may be impacted if you do not accept these cookies. Consent to all Advertising Cookies Advertising Cookies Provider Description Enabled Google Analytics Google Analytics is a web analytics service offered by Google that tracks and reports website traffic. Cookie Information Privacy Policy Terms and Conditions Consent to cookies from provider GoogleAnalytics