Intern Cell Molecular Science

Job description

At Genmab, we are dedicated to building extra[not]ordinary® futures, together, by developing antibody products and groundbreaking, knock-your-socks-off KYSO antibody medicines® that change lives and the future of cancer treatment and serious diseases. We strive to create, champion and maintain a global workplace where individuals’ unique contributions are valued and drive innovative solutions to meet the needs of our patients, care partners, families and employees. Our people are compassionate, candid, and purposeful, and our business is innovative and rooted in science. We believe that being proudly authentic and determined to be our best is essential to fulfilling our purpose. Yes, our work is incredibly serious and impactful, but we have big ambitions, bring a ton of care to pursuing them, and have a lot of fun while doing so. Does this inspire you and feel like a fit? Then we would love to have you join us! Interested in more than one internship with us? We are posting several internship projects at our Utrecht site, each with its own research focus, recruitment team, and selection process. Please explore the available projects and apply to a maximum of two that best match your interests and skills. If you apply to two, include the project titles in order of preference in both motivation letters , with a brief explanation of your interest in each. This helps our teams understand your preferences during the separate selection processes. The Role How can we identify promising antibody variants among thousands of possibilities? And how can we design screening methods that help us find antibodies with specific binding properties? Join our Antibody Discovery and Lead Optimization team at Genmab in Utrecht for a hands-on research internship focused on antibody engineering and screening. Working within Lead Optimization, you will help evaluate and further develop our yeast display platform. This technology displays antibody variants on the surface of yeast cells, allowing researchers to screen large libraries and identify variants with desirable properties. Your project will explore screening strategies for pH-dependent antibodies, investigating how to identify variants whose binding changes under different pH conditions. You will also assess opportunities to improve screening workflows, including the use of magnetic-activated cell sorting (MACS) to enrich antibody libraries. Together with your supervisors, you will refine the research question and experimental plan, taking into account your learning objectives, internship duration, and the team’s ongoing research. You will develop skills in molecular biology, yeast handling, flow cytometry, and data analysis, while learning to connect experimental results to decisions about what to investigate next. You will work alongside experienced colleagues, with guidance and feedback as you take increasing ownership of your project. We welcome students who enjoy asking questions, exploring new approaches, and discussing both promising findings and unexpected results. Responsibilities • Work with your supervisors to develop a research plan and design yeast display experiments to screen antibody libraries for desired binding properties. • Investigate and compare screening strategies for identifying pH-dependent antibodies. • Evaluate ways to improve antibody screening workflows, including MACS-based library enrichment. • Learn and apply relevant molecular biology techniques, yeast handling methods, and flow cytometry workflows. • Analyze, interpret, and visualize experimental datasets containing results from large numbers of antibody variants. • Discuss findings with the team, troubleshoot experimental challenges, and propose follow-up experiments. • Maintain clear and accurate records of your methods, results, and observations. • Present your progress and final conclusions, including the limitations of your findings and recommendations for further research. Requirements • Currently enrolled in a Master’s degree programme at a Dutch university in Molecular Biology, Biotechnology, Immunology, Bioinformatics, or a related field. • The internship must be a formal, mandatory component of your degree programme required for graduation, and you must remain enrolled throughout the placement. Graduates and students seeking an extracurricular internship are not eligible. • A strong interest in antibody biology, protein engineering, and developing experimental technologies. • Basic knowledge of molecular biology techniques, such as PCR and DNA cloning. • An interest in laboratory research and in using experimental data to answer scientific questions. • Basic coding experience, for example in Python or R, is welcome but not required. • A careful, organized approach to experimental work, data analysis, and documentation. • Willingness to contribute ideas, learn from feedback, and discuss challenges or uncertainties with your supervisors. • Able to work collaboratively and develop greater independence as your skills and confidence grow. • Good spoken and written English, enabling you to participate in scientific discussions and explain your findings. General Information • Duration: Preferably 7-10 months, allowing time to develop the project and evaluate its findings. A minimum commitment of 6months is required. • Preferred start date: 1 March 2027, aligned with our internship cohort so you can join fellow students for onboarding and shared learning activities. • Location: Utrecht, Netherlands. • Working arrangement: Full-time, primarily onsite due to the laboratory-based nature of the project. Any opportunities to work remotely will depend on the agreed activities and arrangements with your supervisors. • Project scope: The balance between laboratory work and data analysis will be agreed with your supervisors, considering your learning goals, internship duration, and available experimental data. Intended Recruitment Timeline • Application deadline: 3 December 2026. • Shortlisting and initial screenings: Week commencing 7 December 2026. • Onsite interviews: Week commencing 14 December 2026. • Intended start date: 1 March 2027. The proposed gross annual base salary range for this position, in the primary location, based on a full time schedule is: EUR750,00---750,00 The final salary offer will depend on several factors, including your skills, qualifications, and experience. In addition to base salary, this position is eligible for additional forms of compensation, such as discretionary bonuses and long-term incentives. When you join Genmab, you become a part of a culture that supports your physical, financial, social, and emotional well-being. Our benefits include, but are not limited to: • Pension • Health insurance and wellness benefits • Paid time off • Employee support programs Further details on eligibility for compensation and benefits based on the role will be provided during the recruitment process. About Genmab Genmab is an international biotechnology company with a core purpose to improve the lives of patients through innovative and differentiated antibody therapeutics. For 25 years, its hard-working, innovative and collaborative team has invented next-generation antibody technology platforms and harnessed translational, quantitative and data sciences, resulting in a proprietary pipeline including bispecific T-cell engagers, antibody-drug conjugates, next-generation immune checkpoint modulators and effector function-enhanced antibodies. By 2030, Genmab’s vision is to transform the lives of people with cancer and other serious diseases with Knock-Your-Socks-Off (KYSO®) antibody medicines. Established in 1999, Genmab is headquartered in Copenhagen, Denmark with international presence across North America, Europe and Asia Pacific. For more information, please visit Genmab.com and follow us on LinkedIn and X . Genmab is committed to protecting your personal data and pr