Manager, Product Lifecycle Management (LCM) Execution

Job description

Career CategorySupply ChainJob DescriptionManager, Product Lifecycle Management Execution ABOUT AMGEN Amgen harnesses the best of biology and technology to fight the world’s toughest diseases, and make people’s lives easier, fuller and longer. We discover, develop, manufacture and deliver innovative medicines to help millions of patients. Amgen helped establish the biotechnology industry more than 40 years ago and remains on the cutting-edge of innovation, using technology and human genetic data to push beyond what’s known today. ABOUT THE ROLE Role Description: Let’s do this. Let’s change the world. We are seeking an experienced people leader who thrives in a dynamic, cross-functional environment and is passionate about building high-performing teams that deliver operational excellence across the product lifecycle. In this vital role, you will lead the Lifecycle Management Execution Team, managing a team of approximately 7–8 Senior Associates responsible for the planning, coordination and execution of post-approval Lifecycle Management activities and Change Control implementation across Amgen's commercial portfolio. You will ensure the team delivers timely, compliant and high-quality execution of CMC variations, labeling updates, SKU rationalizations, product discontinuations and other lifecycle initiatives supporting both Regional Supply Chain Operations and Manufacturing Site Operations. Working closely with the Senior Manager, Product Lifecycle Management Capability Lead, Product Lifecycle Teams (PLTs), Regional Operations, Manufacturing Sites, Regulatory Affairs, Quality, Artwork & Labeling and Commercial organizations, you will establish execution priorities, develop organizational capability and continuously improve project delivery performance across the Lifecycle Management portfolio. Roles & Responsibilities: People Leadership Lead, coach and develop a high-performing team of approximately 7–8 Senior Associates responsible for Lifecycle Management execution. Establish clear objectives, priorities and performance expectations aligned with Product Management and Supply Chain objectives. Foster a culture of accountability, collaboration, continuous improvement and customer focus. Develop organizational capability through coaching, mentoring, talent development and succession planning. Manage resource allocation, workload balancing and portfolio prioritization to ensure effective execution and business continuity. Drive employee engagement and create an environment that promotes learning, innovation and operational excellence. Lifecycle Management Execution Oversee the execution of post-approval Lifecycle Management activities across Amgen's commercial portfolio. Ensure successful delivery of CMC variations, labeling changes, SKU rationalizations, product discontinuations and other lifecycle initiatives. Translate Product Lifecycle Team (PLT) decisions into executable work plans and coordinate implementation across the Lifecycle Management Execution team. Ensure integrated project plans are developed, maintained and executed in alignment with agreed timelines and business priorities. Monitor portfolio progress, proactively manage project risks and remove execution barriers. Ensure consistent application of project management methodologies, governance and best practices across all lifecycle activities. Change Control Execution Lead the execution of Change Controls supporting Lifecycle Management activities in accordance with GMP, regulatory requirements and Amgen procedures. Ensure Change Controls are planned, coordinated, implemented and closed within agreed timelines. Coordinate execution across Manufacturing, Quality, Regulatory Affairs, Supply Chain, Planning and other impacted functions. Monitor Change Control performance, compliance and milestone achievement. Escalate critical risks, issues and delays, driving timely resolution with key stakeholders. Ensure accurate project documentation, execution records and audit readiness. Cross-Functional Collaboration Partner with Product Lifecycle Teams (PLTs), Regional Operations Leads, Manufacturing Sites, Regulatory Affairs, Quality Assurance, Artwork & Labeling, Planning, Procurement and Commercial organizations to ensure successful implementation of lifecycle initiatives. Facilitate cross-functional meetings to monitor execution progress, resolve issues and maintain alignment. Provide regular portfolio updates, performance metrics and risk assessments to Product Management leadership. Support implementation planning for complex lifecycle initiatives requiring coordination across multiple functions and geographies. Build strong collaborative relationships across Regional and Site Operations to ensure successful execution. Operational Excellence & Performance Management Establish and monitor KPIs for Lifecycle Management execution, ensuring delivery against business objectives. Drive continuous improvement of project management practices, governance and execution processes. Standardize tools, templates, methodologies and ways of working across the Lifecycle Management Execution team. Identify opportunities to improve efficiency through process simplification, automation and digital enablement. Promote knowledge sharing and implementation of best practices across the Product Management organization. Support capability development initiatives that improve execution quality, predictability and operational performance. Functional Skills Must-Have Skills: Bachelor's degree in Supply Chain Management, Engineering, Life Sciences, Business or a related discipline. 8+ years of experience in pharmaceutical Supply Chain, Manufacturing, Product Lifecycle Management, Regulatory Affairs or Project Management. Previous experience leading project managers or operational teams in a matrixed environment. Demonstrated experience managing complex portfolios and multiple concurrent projects. Strong knowledge of post-approval Lifecycle Management processes, CMC variations, labeling changes and Change Control execution. Experience working in GMP-regulated pharmaceutical manufacturing environments. Strong project management, stakeholder management and organizational leadership skills. Excellent analytical, communication and problem-solving capabilities. Good-to-Have Skills: Experience working within Product Lifecycle Teams (PLTs). Knowledge of pharmaceutical commercialization processes. Experience with SAP, project portfolio management tools and Smartsheet/MS Project. Lean, Six Sigma or Operational Excellence experience. Project Management certification (PMP, PRINCE2 or equivalent). Professional Certifications Preferred: Master’s degree in Supply Chain Management, Engineering, Business, or related field. PMP, PRINCE2 or equivalent Project Management certification. Lean Six Sigma Green Belt or equivalent Operational Excellence certification. Soft Skills: Strong verbal and written communication skills. Proven people leadership and coaching capabilities. Excellent stakeholder management and influencing skills. Strong planning, prioritization and organizational skills. Ability to lead multiple priorities in a fast-paced environment. High degree of initiative, accountability and ownership. Strong analytical and decision-making capabilities. Ability to navigate ambiguity and lead through change. Collaborative leadership style with a continuous improvement mindset. EQUAL OPPORTUNITY STATEMENT Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. We will ensure that individuals with disabilities are provided with reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. .